<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">neurojour</journal-id><journal-title-group><journal-title xml:lang="ru">Неврологический журнал имени Л.О. Бадаляна</journal-title><trans-title-group xml:lang="en"><trans-title>L.O. Badalyan Neurological Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2686-8997</issn><issn pub-type="epub">2712-794X</issn><publisher><publisher-name>ФГАУ «НМИЦ здоровья детей» Минздрава России</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.46563/2686-8997-2021-2-2-73-82</article-id><article-id custom-type="elpub" pub-id-type="custom">neurojour-41</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Алгоритм диагностики нарушений дыхания во сне у детей с неврологической патологией</article-title><trans-title-group xml:lang="en"><trans-title>Algorithm for the diagnosis of breathing disorders during sleep in children with neurological pathology</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7900-5394</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лебедев</surname><given-names>Владислав Витальевич</given-names></name><name name-style="western" xml:lang="en"><surname>Lebedev</surname><given-names>Vladislav V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Младший научный сотрудник, врач функциональной диагностики ФГАУ «НМИЦ здоровья детей» Минздрава России.</p><p>e-mail: vladlv89@mail.ru</p></bio><bio xml:lang="en"><p>MD, junior researcher, functional diagnostic doctor, National Medical Research Center of Children’s Health Russian Federation</p><p>у-mail: vladlv89@mail.ru</p></bio><email xlink:type="simple">vladlv89@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8562-6851</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кожевникова</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kozhevnikova</surname><given-names>Olga V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Газарян</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gazaryan</surname><given-names>Andrey A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Айсина</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Aysina</surname><given-names>Victoriya A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5366-894X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абашидзе</surname><given-names>Э. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Abashidze</surname><given-names>Eka A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузенкова</surname><given-names>Л. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuzenkova</surname><given-names>Lyudmila M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пак</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Pak</surname><given-names>Lale A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Филимонова</surname><given-names>И. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Filimonova</surname><given-names>Irina K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Scopus Author ID: 57215553705</p></bio><bio xml:lang="en"><p>Scopus Author ID: 57215553705</p></bio><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФГАУ «Национальный медицинский исследовательский центр здоровья детей» Минздрава России<country>Россия</country></aff><aff xml:lang="en">National Medical Research Center for Children’s Health<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>19</day><month>07</month><year>2021</year></pub-date><volume>2</volume><issue>2</issue><fpage>73</fpage><lpage>82</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лебедев В.В., Кожевникова О.В., Газарян А.А., Айсина В.А., Абашидзе Э.А., Кузенкова Л.М., Пак Л.А., Филимонова И.К., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Лебедев В.В., Кожевникова О.В., Газарян А.А., Айсина В.А., Абашидзе Э.А., Кузенкова Л.М., Пак Л.А., Филимонова И.К.</copyright-holder><copyright-holder xml:lang="en">Lebedev V.V., Kozhevnikova O.V., Gazaryan A.A., Aysina V.A., Abashidze E.A., Kuzenkova L.M., Pak L.A., Filimonova I.K.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.neuro-journal.ru/jour/article/view/41">https://www.neuro-journal.ru/jour/article/view/41</self-uri><abstract><sec><title>Введение</title><p>Введение. Нарушения сна у детей с патологией нервной системы более выражены, чем в общей популяции. Одной из самых распространённых причин расстройств сна у детей является нарушение дыхания во сне. Целью исследования являлось создание алгоритма диагностики нарушения дыхания во сне у детей с неврологической патологией.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Проанализированы результаты ночных исследований (160 полисомнографий, 98 кардиореспираторных мониторингов), проведённых в отделении инструментальной диагностики ФГАУ «НМИЦ здоровья детей» Минздрава России у 258 детей (154 мальчика и 104 девочек в возрасте от 1 мес до 17 лет) с неврологической патологией. Для оценки качества сна применялись опросники. Важным критерием разделения детей на группы было наличие челюстно-лицевых аномалий. Результаты сопоставлялись с жалобами по опросникам, возрастом, индексом массы тела и ЛОР-статусом пациентов.</p></sec><sec><title>Результаты</title><p>Результаты. В общей выборке получена значимая (р &lt; 0,001) связь нарушений дыхания с жалобами и наличием ЛОР-патологии. Самые тяжёлые нарушения дыхания регистрировались у детей с челюстно-лицевыми аномалиями (р &lt; 0,001). Результатом явилось создание алгоритма обследования детей с неврологической патологией.</p></sec><sec><title>Заключение</title><p>Заключение. Дети с патологией нервной системы при нарушении дыхания во сне требуют персонализированного подхода к коррекции причин этих нарушений в зависимости от нозологии. Хроническая патология ЛОР-органов усугубляет дыхательные нарушения во сне. Регулярное мониторирование нарушений сна по опросникам должно быть включено в алгоритм ведения детей с неврологическими заболеваниями всех возрастов для раннего выявления этих нарушений.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Sleep disorders in children with nervous system pathology are more pronounced than in the general population. One of the most common causes of sleep disorders in children is sleep-disordered breathing. The aim of our study was to create an algorithm for the diagnosis of sleep breathing disorders in children with neurological pathology. </p></sec><sec><title>Materials and methods</title><p>Materials and methods. The results of night studies (160 polysomnographies, 98 cardiorespiratory monitorings) carried out in the department of instrumental diagnostics at the National Medical Research Center for Children’s Health in 258 children (154 boys and 104 girls, aged one month to 17 years) with neurological pathology were analyzed. Questionnaires were used to assess the quality of sleep. An essential criterion for dividing children into groups was the presence of maxillofacial anomalies (MFA). The results were compared with complaints according to questionnaires, age, BMI and ENT-status of patients. </p></sec><sec><title>Results</title><p>Results. In the general sample, a significant (p &lt; 0.001) relationship between respiratory disorders and complaints and the presence of ENT pathology was obtained. The most severe breathing disorders were recorded in children with MFA (p &lt; 0.001). The result was the creation of an algorithm for examining children with neurological pathology. </p></sec><sec><title>Conclusion</title><p>Conclusion. Children with neurological pathology in sleep-breathing disorders require a personalized approach to correcting the causes of these disturbances, depending on the nosology. Chronic pathology of the ENT organs aggravates respiratory disorders during sleep. Regular monitoring of sleep disorders using questionnaires should be included in the algorithm for managing children with neurological diseases of all ages for early detection of these disorders.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>синдром апноэ сна</kwd><kwd>патология нервной системы</kwd><kwd>нарушения сна</kwd><kwd>полисомнография</kwd><kwd>кардиореспираторный мониторинг</kwd><kwd>ЛОР-патология</kwd><kwd>челюстно-лицевые аномалии</kwd></kwd-group><kwd-group xml:lang="en"><kwd>sleep apnea syndrome</kwd><kwd>nervous system pathology</kwd><kwd>sleep disorders</kwd><kwd>polysomnography</kwd><kwd>cardiorespiratory monitoring</kwd><kwd>ENT pathology</kwd><kwd>maxillofacial abnormalities</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Young T., Peppard P.E., Gottlieb D.J. Epidemiology of obstructive sleep apnea: a population health perspective. Am. J. Respir. Crit. Care. Med. 2002; 165(9): 1217-39. https://doi.org/10.1164/rccm.2109080</mixed-citation><mixed-citation xml:lang="en">Young T., Peppard P.E., Gottlieb D.J. Epidemiology of obstructive sleep apnea: a population health perspective. Am. J. Respir. Crit. Care. Med. 2002; 165(9): 1217–39. https://doi.org/10.1164/rccm.2109080</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Garcia J., Wical B., Wical W., Schaffer L., Wical T., Wendorf H., et al. Obstructive sleep apnea in children with cerebral palsy and epilepsy. Dev. Med. Child. Neurol. 2016; 58(10): 1057-62. https://doi.org/10.1111/dmcn.13091</mixed-citation><mixed-citation xml:lang="en">Garcia J., Wical B., Wical W., Schaffer L., Wical T., Wendorf H., et al. Obstructive sleep apnea in children with cerebral palsy and epilepsy. Dev. Med. Child. Neurol. 2016; 58(10): 1057–62. https://doi.org/10.1111/dmcn.13091</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Chaiard J., Weaver T.E. Update on research and practices in major sleep disorders: part i. obstructive sleep apnea syndrome. J. Nurs. Scholarsh. 2019; 51(5): 500-8. https://doi.org/10.1111/jnu.12489</mixed-citation><mixed-citation xml:lang="en">Chaiard J., Weaver T.E. Update on Research and Practices in Major Sleep Disorders: Part I. Obstructive Sleep Apnea Syndrome. J. Nurs. Scholarsh. 2019; 51(5): 500–8. https://doi.org/10.1111/jnu.12489</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Alexiou S., Brooks L.J. Congenital disorders affecting sleep. Sleep Med. Clin. 2012; 7(4): 689-702.</mixed-citation><mixed-citation xml:lang="en">Alexiou S., Brooks L.J. Congenital Disorders Affecting Sleep. Sleep Med. Clin. 2012; 7(4): 689–702.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Crump C., Friberg D., Li X., Sundquist J., Sundquist K. Preterm birth and risk of sleep-disordered breathing from childhood into mid-adulthood. Int. J. Epidemiol. 2019; 48(6): 2039-49. https://doi.org/10.1093/ije/dyz075</mixed-citation><mixed-citation xml:lang="en">Crump C., Friberg D., Li X., Sundquist J., Sundquist K. Preterm birth and risk of sleep-disordered breathing from childhood into mid-adulthood. Int. J. Epidemiol. 2019; 48(6): 2039–49. https://doi.org/10.1093/ije/dyz075</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Stores G. Sleep and Its Disorders in Children and Adolescents with a Neurodevelopmental Disorder: a Review and Clinical Guide. Cambridge: Cambridge University City; 2014.</mixed-citation><mixed-citation xml:lang="en">Stores G. Sleep and Its Disorders in Children and Adolescents with a Neurodevelopmental Disorder: a Review and Clinical Guide. Cambridge: Cambridge University City; 2014.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Marcus C.L., Brooks L.J., Draper K.A., Gozal D., Halbower A.C., Jones J., et al. Diagnosis and management of childhood obstructive sleep apnea syndrome. Pediatrics. 2012; 130(3): e714-55. https://doi.org/10.1542/peds.2012-1672</mixed-citation><mixed-citation xml:lang="en">Marcus C.L., Brooks L.J., Draper K.A., Gozal D., Halbower A.C., Jones J., et al. Diagnosis and management of childhood obstructive sleep apnea syndrome. Pediatrics. 2012; 130(3): e714–55. https://doi.org/10.1542/peds.2012-1672</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Berry R.B., Budhiraja R., Gottlieb D.J., Gozal D., Iber C., Kapur V.K., et al. Rules for scoring respiratory events in sleep: update of the 2007 AASM manual for the scoring of sleep and associated events. j. Clin. Sleep Med. 2012; 8(5): 597-619. https://doi.org/10.5664/jcsm.2172</mixed-citation><mixed-citation xml:lang="en">Berry R.B., Budhiraja R., Gottlieb D.J., Gozal D., Iber C., Kapur V.K., et al. Rules for scoring respiratory events in sleep: update of the 2007 AASM manual for the scoring of sleep and associated events. J. Clin. Sleep Med. 2012; 8(5): 597–619. https://doi.org/10.5664/jcsm.2172</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Sheldon S.H., Ferber R., Kryger M.H., Gozal D., eds. Principles and Practice of Pediatric Sleep Medicine. Elsevier Health Sciences; 2014.</mixed-citation><mixed-citation xml:lang="en">Sheldon S.H., Ferber R., Kryger M.H., Gozal D., eds. Principles and Practice of Pediatric Sleep Medicine. Elsevier Health Sciences; 2014.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Felix O., Amaddeo A., Olmo Arroyo J., Zerah M., Puget S., Cormier- Daire V., et al. Central sleep apnea in children: experience at a single center. Sleep Med. 2016; 25: 24-8. https://doi.org/10.1016/j.sleep.2016.07.016</mixed-citation><mixed-citation xml:lang="en">Felix O., Amaddeo A., Olmo Arroyo J., Zerah M., Puget S., Cormier-Daire V., et al. Central sleep apnea in children: experience at a single center. Sleep Med. 2016; 25: 24–8. https://doi.org/10.1016/j.sleep.2016.07.016</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">ВОЗ. Ожирение и избыточный вес. Информационный бюллетень; 2016. Available at: https://www.who.int/mediacentre/factsheets/fs311/ru/</mixed-citation><mixed-citation xml:lang="en">WHO. Obesity and overweight. Fact sheets; 2016. Available at: https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Полуэктов М.Г., ред. Сомнология и медицина сна: национальное руководство памяти. М.: Медфорум; 2016.</mixed-citation><mixed-citation xml:lang="en">Poluektov M.G., ed. Somnology and Sleep Medicine: a National Memory Guide [Somnologiya i meditsina sna: natsional’noe rukovodstvo pamyati]. Moscow: Medforum; 2016. (in Russian)</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
